Greg Wise was born in Newcastle-upon-Tyne and studied architecture in Edinburgh before moving to Glasgow to study drama at the Royal Scottish Academy of Music and Drama. His first professional job as a performer was in the Jack Good musical Good Rockin' Tonight in 1992, and he has appeared in a variety of television series and movies, but he made his big-screen debut in Christopher Menaul's film of H.E. Bates' mystery drama Feast of July in 1995. The same year saw the release of Ang Lee's film of Jane Austen's Sense and Sensibility, starring and written for the screen by his future wife, Emma Thompson, and in which he played John Willoughby.
His next cinema outing was in Sebastian Gutierrez' thriller Judas Kiss (1998), starring Emma, Alan Rickman and Carla Gugino and, in 2003, he starred as Agent One, with Rowan Atkinson as inept superspy Johnny English, in the box-office hit comedy. He joined the extensive cast of Michael Winterbottom's Tristram Shandy: A Cock and Bull Story (2005), starring Steve Coogan and Rob Bryden and appeared as a disreputable travel writer (and suspected assassin) in Three Days In Havana (2013), also starring in the feel-good '80s musical Walking on Sunshine (2014), filmed in southern Italy.
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